MRX Thrombin Time

Two different lyophilised reagents for detection of fibrinogen abnormalities, and the presence of heparin and other thrombin inhibitors in human citrated plasma.

Thrombin Time (TT) is a common clotting test used to detect functional abnormalities of fibrinogen, and the presence of heparin and other thrombin inhibitors in human citrated plasma.

Medirox has developed two different TT reagents in order to meet different instrument performances and market requirements. MRX TT reagents are both characterised by a high ability to detect unfractioned heparin in plasma samples, indicating that MRX TT reagents are useful as screening tests for plasma samples contaminated with heparin due to an inappropriate use of heparinised needles.

High precision: Total CV ≤ 2,5 %

Excellent stability, up to 8 days reconstituted

High flexibility, multiple reconstitution volumes and
sample to reagent ratio

Sensitivity & Specificity

Details & typical data

Parameters MRX941-5 MRX941-5 MRX945-2
Available volumes: 2 mL reconstituted 5 mL reconstituted 2 mL reconstituted
Product form: Lyophilised Lyophilised Lyophilised
Origin: Bovine thrombin and bovine albumin Bovine thrombin and bovine albumin Bovine thrombin and bovine albumin
Additional products needed: • Diluent (GHI154) or CLSI CLRW type water or equivalent
• Eximius Control Basic or Plus (L1) (MRX170, MRX180)
• No calibration required
• Diluent (GHI154) or CLSI CLRW type water or equivalent
• Eximius Control Basic or Plus (L1) (MRX170, MRX180)
• No calibration required
• Diluent (GHI154) or CLSI CLRW type water or equivalent
• Eximius Control Basic or Plus (L1) (MRX170, MRX180)
• No calibration required
Expected values: 7,8-8,3 sec 15,4-18,8 sec 10,0-15,2 sec
Heparin sensitivity: 0,03‑0,25 IU/mL N/A 0,03‑2 IU/mL
No interferences with: Triglycerides <0,625 g/L Bilirubin* Hemoglobin Triglycerides <3,75 g/L Bilirubin* Hemoglobin* Triglycerides <1,25 g/L Bilirubin <500 mg/L Hemoglobin <2,5 g/L
*Haemolysed or Icteric plasma should not be assayed

Stability & storage

Parameters MRX941-5 (2mL) MRX941-5 (5mL) MRX945-2
Storage: 2-8 ºC 2-8 ºC 2-8 ºC
Shelf-life: 24 months at 2-8 ºC 24 months at 2-8 ºC 24 months at 2-8 ºC
Reconstituted solution: 8 days at 2-8 °C 8 days at 2-8 °C 7 days at 2-8 °C
2 days at 25 °C

Ordering information

Ref. No Product description Size
MRX941-5 MRX Thrombin Time 10x5mL
MRX945-2 MRX Thrombin Time Plus 10x2 mL
MRX171 Eximius Control Basic Level 1 10x1 mL
MRX181 Eximius Control Plus Level 1 10x1 mL
GHI154 Diluent (CLSI CLRW type water) 10x5 mL
 
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